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Manage LD clumping on the SNP analysis
Whether to search through pre-clumped dataset or to re also-extract and you may clump directly from the fresh server. Functions very first multivariable MR study out of Burgess et al 2015.For each and every coverage the outcomes is actually residualised the almost every other exposures, following unweighted regression try applied. The new standard multiplicative arbitrary effects IVW guess.The product quality mistake are corrected for less than dispersionUse the brand new mr_ivw_mre() setting for quotes which do not right for under dispersion. Ensure that he could be founded for the exact same impression allele because the summary dataset. So you can perform MR the result away from a SNP to the a result and you can publicity should be harmonised to help you berelative on the same allele.
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